Chev Chelios, played by Jason Statham, awakens in his home in a drunken state and only to find out that he has been poisoned by a fatal drug, the Beijing cocktail. The catch, to slow down the affect of the drug Chev must keep is adrenaline flowing through his veins.
Chev, his life basically on a timer, goes on a rampage keeping his adrenaline up with crazy stunts and injection of epineferine only to buy enough time to get those who has poisoned him.
Crank is somewhere along the lines of the Transporter meets Speed. The action is non-stop and will keep you on the edge of your seat.